Zininzi iindlela zokunciphisa imigca emihle kunye nemibimbi, kodwa enye yeyona ndlela isebenzayo ngokusebenzisa i-neuromodulators.I-Dysport® (i-abobotulinumtoxinA) yenye yezona zinto zidume kakhulu kwi-neurotoxins kwimarike.Yinaliti kagqirha yabantu abadala abangaphantsi kweminyaka engama-65 ubudala.Ibonakaliswe ukuba inceda okwethutyana ukugudisa okuphakathi ukuya kwimigca eshwabene kakhulu phakathi kwamashiya.Le yingxaki uninzi lwethu oluzama ukuyisombulula.
Njengalo naliphi na iyeza, kukho iziphumo ebezingalindelekanga.KwiDysport, ezona ziphumo bezingalindelekanga zixhaphakile kukucaphuka kwempumlo kunye nomqala, intloko ebuhlungu, iintlungu kwindawo ebekuhlatywe kuyo inaliti, ukusabela kolusu kwindawo ebekuhlatywe kuyo inaliti, usulelo lwendlela yokuphefumla ephezulu, ukudumba kwenkophe, ukuthotywa kweenkophe, sinusitis, kunye nesicaphucaphu.(Gqibezela ulwazi olubalulekileyo lokhuseleko, kubandakanywa nezilumkiso zebhokisi emnyama malunga nokuhanjiswa komgama omde weziphumo ze-toxin, ziyafumaneka ekupheleni kweli nqaku.)
Nangona wonke umntu uyazi ukuba iDysport inokugudisa imibimbi, ineminye imisebenzi emininzi.Apha, siye sahlulahlula iinyaniso ezili-10 ezibalulekileyo malunga nokutofa ukuze ukwazi ukuthatha isigqibo sokuba ikulungele na.
I-Dysport iphatha okwexeshana imigca ephakathi ukuya kobunzima phakathi kwamashiya ngokunciphisa umsebenzi othile wezihlunu, kuba imibimbi ibangelwa kukuzilolonga ngokuphindaphindiweyo kunye nokucutheka kwemisipha.1 Isitofu esinye kumanqaku amahlanu phakathi nangaphezulu kwamashiya sinokunqanda okwethutyana ukushwabana kwezihlunu ezibangela imigca efingeyo.Ekubeni kukho ukuhamba okuncinci kwindawo, imigca ayinakwenzeka ukuba iphuhlise okanye inzulu.
Ngokutsho kweengxelo, i-Dysport inokuvelisa iziphumo kwiintsuku ezimbini ukuya kwezintathu kuphela emva kwe-10 ukuya kwimizuzu engama-20 yonyango.I-2-4 Oku kunika ukuguquguquka ngakumbi kwizigulane ezifuna iziphumo xa zicwangcisa amalungiselelo e-cosmetic kwiziganeko okanye iindibano zoluntu.
I-Dysport ayiqali ngokukhawuleza, * 2-4, kodwa ihlala ixesha elide.Ngapha koko, iDysport inokuhlala ukuya kuthi ga kwiinyanga ezintlanu.† 2,3,5.
* Isiphelo sesibini sisekwe kuqikelelo lweKaplan-Meier lwexesha eliqokelelweyo lokuphendula.I-GL-1 (i-Dysport 55/105 [52%], i-placebo 3/53 [6%]) kunye ne-GL-2 (i-Dysport 36/71 [51%], i-placebo 9/71 [13%]) kunye ne-GL- 32 iintsuku (Dysport 110/200 [55%], placebo 4/100 [4%]).† I-GL-1 kunye ne-GL-3 izifundo ezivavanyiweyo ubuncinane iintsuku ze-150 emva kwonyango.Ngokusekelwe kusetyenziso lwedatha evela kwizifundo ezimbini eziziimfama eziphindwe kabini, ezingahleliwe, ezilawulwa yi-placebo (i-GL-1, i-GL-3) kuhlalutyo lwe-post-hoc, i-GLSS iphuculwe nge-≥ inqanaba le-1 ukusuka kwisiseko.
"NgeDysport-kwaye ngokuqinisekileyo iisirinji zobuchwephesha-kufuneka ulindele into esiyibiza ngokuba yi-softening of wrinkles eguquguqukayo: imibimbi eyenza i-muscle movement kunye ne-contraction," kuchaza u-Omer Ibrahim, MD, i-Chicago dermatologist."Kuya kufuneka ulindele ukuthamba kwemigca ephakathi ukuya kobukhali bebunzi ngelixa ugcina inkangeleko yakho yendalo."
"I-Dysport ayinakukwazi ukususa ngokupheleleyo imibimbi enzulu ye-static, eyimibimbi ekhoyo xa iphumla ngaphandle kokuphazamiseka kwemisipha," kusho uDkt Ibrahim.Le migca inzulu ebonakalayo xa ubuso buphumle idla ngokufuna unyango olunzulu lwe-ofisi ukuphucula inkangeleko yayo."Ngokuqinisekileyo, i-Dysport ayinakusetyenziswa njengento yokuzalisa, oku kuthetha ukuba akuyi kunceda ukuqhekeka kobuso obunzulu kunye noxinzelelo olufana ne-cheekbones, imilomo kunye nemigca yokumomotheka," wongezelela uDkt Ibrahim.
I-Dysport ibonakaliswe ngokukodwa ukuba iyasebenza ekuphuculeni okwethutyana ukubonakala kwemibimbi kwindawo yenkxalabo eqhelekileyo: phakathi kwamashiya.Ukuba ayiphathwa, le migca ishwabeneyo phakathi kwamashiya inokwenza abantu babonakale benomsindo kwaye badiniwe.
Ukunciphisa ukucutha kwemisipha ethile enokubangela imigca emihle kunye nemibimbi phakathi kwamashiya, isirinji yakho iya kufaka iDysport kwiindawo ezikhethekileyo ezintlanu: inaliti enye phakathi kwamashiya kunye nenaliti ezimbini ngaphezulu kweshiya ngalinye.
Ekubeni ngokuqhelekileyo kusetyenziswa amanqaku enaliti amahlanu kuphela, unyango lweDysport lukhawuleza kakhulu.Yonke le nkqubo ithatha kuphela malunga nemizuzu eyi-10 ukuya kwe-20.Ngapha koko, ikhawuleza kakhulu kangangokuba unokwenza idinga ngexesha lesidlo sasemini kuba akufuneki ube nexhala lokushiya umsebenzi ixesha elide.
"Iindaba ezimnandi kukuba abantu abaninzi bangabaviwa abafanelekileyo beDysport," utshilo uGqr. Ibrahim.Eyona ndlela yokwazi ukuba olu nyango lukulungele na kukuxoxa ngeDysport nomboneleli wakho.Ukuba awudibani neprotein yobisi okanye naliphi na elinye icandelo leDysport, alajiki kuyo nayiphi na i-neuromodulator okanye naliphi na elinye icandelo, okanye unosulelo kwindawo ecetywayo yokutofa, iDysport ayifanelanga wena.UDkt Ibrahim wongezelela: "Abantu abafanele baphephe i-Dysport ngabo bakhulelweyo ngoku, abancancisayo, abangaphezu kweminyaka engama-65, okanye banobuthathaka obunzima bemisipha kunye nezinye izifo ze-neurological."
"I-Dysport isetyenziselwe ukuphelisa imibimbi yobuso iminyaka emininzi, kwaye ukhuseleko kunye nokusebenza kwayo kuye kwabonakaliswa kwizifundo kunye nezigulane emhlabeni jikelele6," uDkt Ibrahim waqinisekisa.Kwizandla ezichanekileyo, iDysport iya kuvelisa iziphumo ezifihlakeleyo, zendalo.
I-Dysport® (i-abobotulinumtoxinA) yinaliti kagqirha esetyenziselwa ukuphucula okwethutyana ukubonakala kwemigca ephakathi ukuya kweyona inzima (imigca ephakathi) phakathi kwamashiya abantu abadala abangaphantsi kweminyaka engama-65 ubudala.
Loluphi olona lwazi lubalulekileyo ekufuneka uyazi malunga neDysport?Ukusasazeka kweziphumo ze-toxin: Kwezinye iimeko, iziphumo ze-Dysport kunye nazo zonke iimveliso ze-toxin ye-botulinum zinokuchaphazela iindawo zomzimba kude nendawo yokutofa.Iimpawu zinokuthi zenzeke kwiiyure ukuya kwiiveki emva kwesitofu kwaye zinokubandakanya ukuginya kunye neengxaki zokuphefumla, ubuthathaka ngokubanzi kunye nobuthathaka bemisipha, ukubona kabini, ukubona okubonakalayo kunye neenkophe ezithobileyo, ukuhlaza okanye ukutshintsha okanye ukulahlekelwa kwelizwi, ubunzima bokuthetha ngokucacileyo, okanye ukulahlekelwa ukulawula isinyi. .Iingxaki zokuginya nokuphefumla zinokubeka ubomi esichengeni, kwaye ukufa kuye kwachazwa.Ukuba ezi ngxaki bezikhona phambi kokutofa, ungoyena mngcipheko mkhulu.
Ezi ziphumo zisenokwenza ukuba ungakhuselekanga kuwe ukuqhuba imoto, ukusebenzisa oomatshini, okanye ukwenza ezinye izinto eziyingozi.
Musa ukufumana unyango lwe-Dysport ukuba unayo: i-allergies kwi-Dysport okanye naziphi na izithako zayo (jonga uluhlu lwezithako ekupheleni kwesikhokelo seziyobisi), ukungahambi kakuhle kwiiprotheni zobisi, ukusabela okwenyukayo kuyo nayiphi na enye imveliso ye-toxin ye-botulinum, njengeMyobloc®, I-Botox® okanye i-Xeomin®, inosulelo lwesikhumba kwindawo ecetywayo yokutofa, ingaphantsi kweminyaka eli-18 ubudala, okanye ikhulelwe okanye incancisa.
Idosi yeDysport yahlukile kwidosi yayo nayiphi na enye imveliso yetyhefu ye-botulinum kwaye ayinakuthelekiswa nedosi yayo nayiphi na enye imveliso onokuthi uyisebenzise.
Tshela ugqirha wakho malunga naluphi na ukugwinya okanye ubunzima bokuphefumla kunye nazo zonke izihlunu zakho okanye iimeko ze-nerve, ezifana ne-amyotrophic lateral sclerosis [ALS okanye isifo sikaLou Gehrig], i-myasthenia gravis okanye i-Lambert-Eaton syndrome, enokunyusa umngcipheko wemiphumo emibi kakhulu , Kubandakanya ubunzima. ukuginya kunye nobunzima bokuphefumla.Ukwalana okumandundu kunokwenzeka xa usebenzisa iDysport.Amehlo omileyo nawo axelwe.
Xelela ugqirha wakho ngazo zonke iimeko zonyango lwakho, kubandakanywa nokuba kukho utshintsho kuqhaqho ebusweni bakho, izihlunu kwindawo yonyango zibuthathaka kakhulu, nokuba kukho utshintsho olungaqhelekanga ebusweni, ukudumba kwindawo ebekuhlatywe kuyo inaliti, ukuthotywa iinkophe okanye inkophe eyehlayo. ukugoba, amanxeba anzulu ebusweni, ulusu olutyebileyo olune-Oyile, imibimbi engakwaziyo ukugudisa ngokuyahlula, okanye ukuba ukhulelwe okanye uncancisa okanye uceba ukukhulelwa okanye ukuncancisa.
Xelela ugqirha wakho malunga nawo onke amayeza owathathayo, kubandakanywa amayeza kagqirha kunye namayeza angaphaya kwe-counter-the-counter, iivithamini, imifuno, kunye nezinye iimveliso zendalo.Ukusebenzisa iDysport namanye amayeza kunokubangela iziphumo ebezingalindelekanga ezimandundu.Xa uthatha iDysport, musa ukuqala nawaphi na amayeza amatsha ngaphandle kokubonisana nogqirha wakho kuqala.
Ngokukodwa, xelela ugqirha wakho ukuba uneemeko ezilandelayo: Kwiinyanga ezine ezidlulileyo okanye nangaliphi na ixesha elidlulileyo (qiniseka ukuba ugqirha wakho uyazi kakuhle ukuba yeyiphi imveliso oyifumeneyo, iinaliti zamva nje ze-antibiotics, iziphumlisi zemisipha , Thatha i-allergies okanye iyeza elibandayo. okanye uthathe iipilisi zokulala.
Ezona ziphumo bezingalindelekanga zixhaphake kakhulu kukurhawuzelelwa yimpumlo nomqala, intloko ebuhlungu, iintlungu kwindawo ebekuhlatywe kuyo inaliti, ukusabela kolusu kwindawo ebekuhlatywe kuyo inaliti, usulelo lomjelo wokuphefumla ophezulu, ukudumba kwenkophe, ukuthotywa kwenkophe, sinusitis, kunye nesicaphucaphu.
Ixesha lokuposa: Aug-23-2021